Subjective Cognitive Decline‐Plus: Longitudinal Assessment and Risk for Cognitive Impairment
In a community setting, SCD reflecting "SCD plus" features increased the risk of future MCI, AD, and all-cause dementia with about the same HR estimated in clinic-based settings. SCD may be an independent clinically expressed risk factor for preclinical AD and other dementias beyond the risk incurred by APOE ε4 and AD PRS.
Authors
- Sanford H. Auerbach (ORCID: https://orcid.org/0000-0003-2962-6405)
- Moon-Il Kang (ORCID: https://orcid.org/0000-0001-5932-6804)
- Rhoda Au (ORCID: https://orcid.org/0000-0001-7742-4491)
- Ting Fang Alvin Ang (ORCID: https://orcid.org/0000-0003-4687-2552)
- Ashita S. Gurnani
- Lindsay A. Farrer (ORCID: https://orcid.org/0000-0001-5533-4225)
- Sherral Devine (ORCID: https://orcid.org/0000-0002-5063-6651)
- Jessica Spat‐Lemus (ORCID: https://orcid.org/0000-0001-6126-0103)
- Wei Qiao Qiu (ORCID: https://orcid.org/0000-0002-2082-2410)
- Arnav Mahajan (ORCID: https://orcid.org/0000-0002-8303-6636)
- Jiachen Chen (ORCID: https://orcid.org/0000-0002-1941-2326)
- Shruti Durape
- Richard Sherva (ORCID: https://orcid.org/0000-0003-2133-1493)
- Kathryn L. Lunetta (ORCID: https://orcid.org/0000-0002-9268-810X)
- Jesse Mez (ORCID: https://orcid.org/0000-0003-1438-5442)
- Clara Li (ORCID: https://orcid.org/0000-0003-1680-8322)
Institutions
- Boston University (US)
- Montclair State University (US)
- George Washington University (US)
- Framingham Heart Study (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.088004
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.39