‘Latent’ mild behavioral impairment as a potential diagnostic strategy for preclinical Alzheimer’s disease: an animal model study
Taken together, we propose that anxiety-like and depressive-like behaviors can be detected at an early age in 3xTg-AD mice as a 'latent' MBI syndrome, positioning it as a possible diagnostic strategy for preclinical AD.
Authors
- Luiz Roberto Britto (ORCID: https://orcid.org/0000-0003-0563-0645)
- Monique Patrício Singulani (ORCID: https://orcid.org/0000-0001-7019-0485)
- Orestes Vicente Forlenza (ORCID: https://orcid.org/0000-0002-6962-5899)
- Leda Leme Talib (ORCID: https://orcid.org/0000-0001-5866-1993)
- Rosana Camarini (ORCID: https://orcid.org/0000-0002-8131-6108)
Institutions
- Universidade de São Paulo (BR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.087517
- Primary Topic
- Medicinal Plants and Neuroprotection
- Type
- article
- Field-Weighted Citation Impact
- 0.00