Physical Characterisation of pre‐clinical progressive model of Alzheimer’s Disease

Alginate beads are stable over time in a brain-like environment. Furthermore alginate beads of 1.5% Alg and 0.3%M closely match the brain environment. Alginate also causes no significant inflammatory response. Therefore alginate is a suitable carrier for 7PA2 further work must now be done in characterising 7PA2 cells and their amyloid species and the eventual effects in the brain.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.087945
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Physical Characterisation of pre‐clinical progressive model of Alzheimer’s Disease

Bushra Almari, Asif Iqbal
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Physical Characterisation of pre‐clinical progressive model of Alzheimer’s Disease

Bushra Almari, Asif Iqbal
article en

Abstract

Alginate beads are stable over time in a brain-like environment. Furthermore alginate beads of 1.5% Alg and 0.3%M closely match the brain environment. Alginate also causes no significant inflammatory response. Therefore alginate is a suitable carrier for 7PA2 further work must now be done in characterising 7PA2 cells and their amyloid species and the eventual effects in the brain.

Alzheimer s & DementiaVol. 20(S1)
University of Huddersfield (GB)
Openalex Percentile: Top 65%
Alzheimer's disease research and treatments
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Physical Characterisation of pre‐clinical progressive model of Alzheimer’s Disease — Bushra Almari, Asif Iqbal · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS