Phospholipase D3 (PLD3) Regulates Lysosomal Biogenesis
PLD3 plays a role in lysosomal biogenesis. As endolysosomal abnormalities are increasingly appreciated as the causal agent for the pathogenesis of AD, this study may position the PLD3 pathway as a therapeutic target for the treatment of AD.
Authors
- Cristian Carvajal‐Tapia (ORCID: https://orcid.org/0000-0002-5590-6905)
- Wilber Romero‐Fernandez (ORCID: https://orcid.org/0000-0001-9868-8074)
- Alena Shostak
- Matthew Schrag (ORCID: https://orcid.org/0000-0001-7048-0503)
- Yongchao Wang
- Paige Rieschick
- Nathan Appelbaum
Institutions
- Vanderbilt Health (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.087739
- Citations
- 1
- Primary Topic
- Calcium signaling and nucleotide metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.40