Phospholipase gamma2: A candidate genetic risk factor for Alzheimer’s disease that can alter synaptic function in DG‐perforant pathway of hippocampus
Results from the study, reflect critical insight of PLCG2 regulating neuronal and/or synaptic activity, which may underlie the cognitive dysfunction (viz. recognition memory) and synaptic alteration to the PP-DG circuitry seen in AD.
Authors
- Séverine Deforges (ORCID: https://orcid.org/0000-0001-7450-6897)
- Avishek Roy (ORCID: https://orcid.org/0000-0003-2633-487X)
- Christophe Mulle (ORCID: https://orcid.org/0000-0003-2709-6615)
- Anaël Erhardt
Institutions
- Université de Bordeaux (FR)
- Institut Interdisciplinaire de Neuroscience (FR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.084662
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00