Microglial ADGRG1/GPR56 regulates amyloid clearance in Alzheimer’s disease
Our study supports that microglial GPR56 plays an indispensable role in curtailing AD progression, presenting a potential new therapeutic target in combating AD.
Authors
- Xianhua Piao (ORCID: https://orcid.org/0000-0001-7540-6767)
- Beika Zhu (ORCID: https://orcid.org/0000-0003-2210-2772)
- Andi Wangzhou (ORCID: https://orcid.org/0000-0001-5667-1223)
- Lauren Chao
- Diankun Yu (ORCID: https://orcid.org/0000-0002-1390-7985)
- Rachael Schmidt (ORCID: https://orcid.org/0009-0000-6476-5780)
- William W. Seeley (ORCID: https://orcid.org/0000-0003-1410-2027)
- Tao Li (ORCID: https://orcid.org/0000-0002-9174-1271)
- Stacy L. De Florencio
Institutions
- University of California, San Francisco (US)
- University Memory and Aging Center (US)
- Broad Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.084250
- Citations
- 1
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.25