Circulating metabolites and risk of incident dementia: A prospective cohort study

Taken together, circulating levels of L-LDL-CE% and L-LDL-C% were robustly linked to risk of AD and AD phenotypes, but not with VD. S-HDL-CE was associate with lower risk of VD, but not with AD or AD phenotypes. These metabolites may play a role in the advancement of future intervention trials. Additional research is necessary to gain a complete comprehension of the molecular mechanisms behind these associations.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.084495
Primary Topic
Metabolomics and Mass Spectrometry Studies
Type
article
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article

Circulating metabolites and risk of incident dementia: A prospective cohort study

Shu‐Yi Huang
Alzheimer s & Dementia
Metabolomics and Mass Spectrometry Studies
article

Circulating metabolites and risk of incident dementia: A prospective cohort study

Shu‐Yi Huang
article en

Abstract

Taken together, circulating levels of L-LDL-CE% and L-LDL-C% were robustly linked to risk of AD and AD phenotypes, but not with VD. S-HDL-CE was associate with lower risk of VD, but not with AD or AD phenotypes. These metabolites may play a role in the advancement of future intervention trials. Additional research is necessary to gain a complete comprehension of the molecular mechanisms behind these associations.

Alzheimer s & DementiaVol. 20(S1)
Fudan University (CN), Huashan Hospital (CN)
Good health and well-being
Openalex Percentile: Top 78%
Metabolomics and Mass Spectrometry Studies
DOIOpen Access PDFOpenAlex
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Circulating metabolites and risk of incident dementia: A prospective cohort study — Shu‐Yi Huang · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS