Circulating metabolites and risk of incident dementia: A prospective cohort study

Taken together, circulating levels of L-LDL-CE% and L-LDL-C% were robustly linked to risk of AD and AD phenotypes, but not with VD. S-HDL-CE was associate with lower risk of VD, but not with AD or AD phenotypes. These metabolites may play a role in the advancement of future intervention trials. Additional research is necessary to gain a complete comprehension of the molecular mechanisms behind these associations.