Immature and mature pathological tau forms in the retina of MCI and AD patients correlate with brain tauopathy
Our data demonstrate that most forms of retinal tauopathy are increased in early AD and correlate with one or more AD neuropathology and cognitive parameters, encouraging the development of retinal tauopathy imaging for AD detection and monitoring disease progression.
Authors
- Rakez Kayed (ORCID: https://orcid.org/0000-0001-6216-8640)
- Keith L. Black (ORCID: https://orcid.org/0000-0002-0546-4934)
- Julie A. Schneider (ORCID: https://orcid.org/0000-0002-9482-1752)
- Altan Rentsendorj (ORCID: https://orcid.org/0009-0001-4322-8107)
- Maj‐Linda B. Selenica (ORCID: https://orcid.org/0000-0001-9570-8172)
- Edward Robinson (ORCID: https://orcid.org/0000-0001-8262-2281)
- Nazanin Mirzaei (ORCID: https://orcid.org/0000-0002-5753-5300)
- Lon S. Schneider (ORCID: https://orcid.org/0000-0002-4636-6150)
- Dieu‐Trang Fuchs
- Maya Koronyo‐Hamaoui (ORCID: https://orcid.org/0000-0003-2864-8442)
- Debra Hawes (ORCID: https://orcid.org/0000-0001-5936-4835)
- Miyah R. Davis
- Daniel C. Lee (ORCID: https://orcid.org/0000-0002-9718-5579)
- Haoshen Shi (ORCID: https://orcid.org/0000-0002-2326-0337)
- Yosef Koronyo
Institutions
- University of Southern California (US)
- Cedars-Sinai Medical Center (US)
- Rush University Medical Center (US)
- University of Kentucky (US)
- The University of Texas Medical Branch at Galveston (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.087770
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00