Examining the associations between Alzheimer disease, Lewy body, and TDP‐43 neuropathology with mild behavioral impairment: a clinicopathological study of older adults

These findings suggest that those with autopsy-confirmed AD-but not other common proteinopathies-are more likely to be preceded by MBI than by NPSnoMBI or noNPS in the five years before death. Among those with MBI, the presence of LB might serve as an important co-pathology in the development of AD dementia. By extension to postmortem diagnosis, these results reinforce the utility of MBI in AD-related dementia prognostication.