Cognitive characteristics in a Uruguayan cohort of healthy subjects with high educational level in risk of development dementia and its relation with ApoE genotype
our results suggest that the CERAD and CERAD Delayed may vary in different APOE allele combinations in normal subjects with a high educational level at risk of dementia in Uruguay. Understanding how genetic variability contributes to individual differences in cognition is important for the design of multidomain assessments and interventions, not only in subjects with cognitive impairment, but also in normal ageing in underrepresented populations.
Authors
- Juan Andrés Abin‐Carriquiry
- Mônica Sanches Yassuda (ORCID: https://orcid.org/0000-0002-9182-2450)
- Margarita García‐Fontes
- Francisco Lopera (ORCID: https://orcid.org/0000-0002-5238-0231)
- R Ferrando (ORCID: https://orcid.org/0000-0001-8317-6332)
- Paulo Caramelli (ORCID: https://orcid.org/0000-0002-4786-6990)
- Lucía Crivelli (ORCID: https://orcid.org/0000-0002-0083-9389)
- Roberto Superchi
- Ana Charamelo
- Cláudia Kimie Suemoto (ORCID: https://orcid.org/0000-0002-5942-4778)
- Ricardo Nitríni (ORCID: https://orcid.org/0000-0002-5721-1525)
- Ana Luisa Sosa (ORCID: https://orcid.org/0000-0003-3930-3618)
- Rosa Maria Salinas‐Contreras
- Florencia Arredondo (ORCID: https://orcid.org/0000-0002-4462-8049)
- Alejandra Amestoy
- Ricardo Allegri (ORCID: https://orcid.org/0000-0001-7166-1234)
- Ismael Luis Calandri (ORCID: https://orcid.org/0000-0002-6983-1430)
- Gustavo Emilio Sevlever (ORCID: https://orcid.org/0000-0002-9567-7553)
- Mercedes Menendez
- Francesca V. Mariani (ORCID: https://orcid.org/0000-0003-1619-8763)
- Laura Reyes
- Laura Uriarte
- Maren Torheim
- Fabian Preciozzi
- Leandro Dansilio
- Laura Bocos
- Lucia Cortabarría
- Alice Leites
- Andrés Damián (ORCID: https://orcid.org/0000-0002-5275-6067)
- Ramón Suárez
- Sergio Dansilio
- Valeria Contreras
- Sofia Santero
- Lina Marcela Vellila
Institutions
- Universidade Federal de Minas Gerais (BR)
- Hospital Británico (UY)
- Universidade de São Paulo (BR)
- Universidad de Antioquia (CO)
- Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia (AR)
- Instituto Universitario Asociación Cristiana de Jóvenes (UY)
- Instituto Nacional de Neurología y Neurocirugía (MX)
- Hospital de Clínicas (UY)
- Centro Uruguayo de Imagenología Molecular (UY)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.089667
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00