Microbiota‐Microglia Interactions Modulate Beta‐Amyloid Levels

Taken together, these data suggest that bacteria in the Bacteroidota phylum contribute to AD pathogenesis by suppressing microglia phagocytic function, leading to impaired Aβ clearance and accumulation of plaques.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.087775
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Microbiota‐Microglia Interactions Modulate Beta‐Amyloid Levels

Laura M. Cox
Alzheimer s & Dementia
Neuroinflammation and Neurodegeneration Mechanisms
article

Microbiota‐Microglia Interactions Modulate Beta‐Amyloid Levels

Laura M. Cox
article en

Abstract

Taken together, these data suggest that bacteria in the Bacteroidota phylum contribute to AD pathogenesis by suppressing microglia phagocytic function, leading to impaired Aβ clearance and accumulation of plaques.

Alzheimer s & DementiaVol. 20(S1)
Brigham and Women's Hospital (US), Harvard University (US)
Openalex Percentile: Top 71%
Neuroinflammation and Neurodegeneration Mechanisms
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Microbiota‐Microglia Interactions Modulate Beta‐Amyloid Levels — Laura M. Cox · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS