The signaling function of CHI3L1/YKL‐40 in neuroinflammation and Alzheimer’s disease

Our findings provide the pioneering evidence for the biological role of CHI3L1 in the brain, departing from its long-regarded role as merely a biomarker. The discoveries we made here would be highly advantageous for the development of much-needed therapeutics to prevent neuroinflammatory toxicity in AD and relevant brain disorders.

Authors

Yu‐Wen Alvin Huang (ORCID: https://orcid.org/0000-0003-4082-8008)

Institutions

Brown University (US)

Publication Details

Journal: Alzheimer s & Dementia
Published: 2024-12-01
DOI: https://doi.org/10.1002/alz.085972
Primary Topic: Studies on Chitinases and Chitosanases
Type: article
Field-Weighted Citation Impact: 0.00

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article

The signaling function of CHI3L1/YKL‐40 in neuroinflammation and Alzheimer’s disease

Yu‐Wen Alvin Huang

Dec 1, 2024

Alzheimer s & Dementia

Studies on Chitinases and Chitosanases

article

The signaling function of CHI3L1/YKL‐40 in neuroinflammation and Alzheimer’s disease

Yu‐Wen Alvin Huang

December 1, 2024article en

Abstract

Alzheimer s & DementiaVol. 20(S1)

Brown University (US)

Good health and well-being

Openalex Percentile: Top 78%

Studies on Chitinases and Chitosanases

DOI Open Access PDF OpenAlex

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The signaling function of CHI3L1/YKL‐40 in neuroinflammation and Alzheimer’s disease — Yu‐Wen Alvin Huang · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS