Butyrate and Lauric acid effect on Astrocytes and Neurons in Alzheimer’s disease
The findings indicate that both butyrate and lauric acid inhibit inflammation in Alzheimer's-induced astrocytes and neurons. Ongoing investigations aim to evaluate their effects on various cytokines and determine the responsible genes through qPCR analysis.
Authors
- Lotta E. Oikari (ORCID: https://orcid.org/0000-0001-7821-8622)
- Prashant Bharadwaj (ORCID: https://orcid.org/0000-0003-4361-9906)
- Vijay Jayasena (ORCID: https://orcid.org/0000-0001-8681-0626)
- Ralph N. Martins (ORCID: https://orcid.org/0000-0002-4828-9363)
- Warnakulasuriya Mary Ann Dipika Binosha Fernando (ORCID: https://orcid.org/0000-0002-8364-7808)
- Senarath Wtpsk (ORCID: https://orcid.org/0000-0003-4909-6296)
Institutions
- Edith Cowan University (AU)
- QIMR Berghofer Medical Research Institute (AU)
- Australian Alzheimer’s Research Foundation (AU)
- Dementia Australia (AU)
- Western Sydney University (AU)
- Macquarie University (AU)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.092277
- Citations
- 1
- Primary Topic
- Fatty Acid Research and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.31