Identification of Protein Tyrosine Phosphatase Receptor Zeta as a Novel Complement C1q Synaptic Interacting Partner

In conclusion, we present data identifying and validating a novel AD-associated C1q synaptic binding partner. Future studies will determine if preventing the synaptic presentation of PTPRZ will rescue synapse loss in models of tauopathy.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.089467
Primary Topic
Neuroinflammation and Neurodegeneration Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Identification of Protein Tyrosine Phosphatase Receptor Zeta as a Novel Complement C1q Synaptic Interacting Partner

Matthew J. Benskey
Alzheimer s & Dementia
Neuroinflammation and Neurodegeneration Mechanisms
article

Identification of Protein Tyrosine Phosphatase Receptor Zeta as a Novel Complement C1q Synaptic Interacting Partner

Matthew J. Benskey
article en

Abstract

In conclusion, we present data identifying and validating a novel AD-associated C1q synaptic binding partner. Future studies will determine if preventing the synaptic presentation of PTPRZ will rescue synapse loss in models of tauopathy.

Alzheimer s & DementiaVol. 20(S1)
Michigan State University (US)
Good health and well-being
Openalex Percentile: Top 71%
Neuroinflammation and Neurodegeneration Mechanisms
DOIOpen Access PDFOpenAlex
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Identification of Protein Tyrosine Phosphatase Receptor Zeta as a Novel Complement C1q Synaptic Interacting Partner — Matthew J. Benskey · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS