Neuronal mTORC1 is required for acute Aβ‐induced cognitive dysfunction
Neuronal mTORC1 is required for acute Aβ-induced cognitive dysfunction. Therefore, reduction of mTORC1 signaling in neurons with systemic rapamycin treatment contributes to the amelioration of Aβ-induced cognitive dysfunction in AD mouse models.
Authors
- Verónica Galván (ORCID: https://orcid.org/0000-0002-4501-8568)
- Kristine Williams (ORCID: https://orcid.org/0000-0003-1312-788X)
- Stacy A. Hussong (ORCID: https://orcid.org/0000-0003-1957-9086)
Institutions
- Oklahoma City VA Health Care System (US)
- University of Oklahoma Health Sciences Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.091116
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00