Differentially expressed genes and biological processes shared by alternative and mouse models of Alzheimer’s disease

The findings suggest that alternative models share transcriptomic similarities with mouse models of amyloidosis. Thus, these models may serve to accelerate the understanding of amyloid-related pathophysiological processes and the development of innovative therapeutics in AD.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.092626
Primary Topic
Bioinformatics and Genomic Networks
Type
article
Field-Weighted Citation Impact
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article

Differentially expressed genes and biological processes shared by alternative and mouse models of Alzheimer’s disease

Eduardo Rigon Zimmer, Giovanna Carello‐Collar, Marco Antônio De Bastiani, Flávia Suelen de Oliveira Pereira et al.
Alzheimer s & Dementia
Bioinformatics and Genomic Networks
article

Differentially expressed genes and biological processes shared by alternative and mouse models of Alzheimer’s disease

Eduardo Rigon Zimmer, Giovanna Carello‐Collar, Marco Antônio De Bastiani, Flávia Suelen de Oliveira Pereira, Daiana Silva Ávila, Vitória Vitalina Margarita Ryssina
article en

Abstract

The findings suggest that alternative models share transcriptomic similarities with mouse models of amyloidosis. Thus, these models may serve to accelerate the understanding of amyloid-related pathophysiological processes and the development of innovative therapeutics in AD.

Alzheimer s & DementiaVol. 20(S1)
Universidade Federal do Rio Grande do Sul (BR), Universidade Federal de Ciências da Saúde de Porto Alegre (BR), Instituto do Cérebro (BR), Universidade Federal do Pampa (BR)
Life in Land
Openalex Percentile: Top 78%
Bioinformatics and Genomic Networks
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Differentially expressed genes and biological processes shared by alternative and mouse models of Alzheimer’s disease — Eduardo Rigon Zimmer, Giovanna Carello‐Collar, et al. · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS