Fatty Acid Amide Hydrolase Single Nucleotide Polymorphism rs324420A/C Associations with Alzheimer’s Disease
Slower rates of cognitive and neuroanatomical decline in amyloid positive patients with MCI or mild dementia due to AD suggest a potential protective role of the rs324420 minor allele in the FAAH gene. Further investigation is warranted, including cognitive, anatomical, fluid biomarker and neuropsychiatric symptom profiles.
Authors
- Shiropa Noor
- Che‐Yuan Wu (ORCID: https://orcid.org/0000-0001-8548-1824)
- Ruth A. Ross
- Walter Swardfager (ORCID: https://orcid.org/0000-0002-0030-8908)
- Daniel K Mori‐Fegan (ORCID: https://orcid.org/0000-0003-1290-7710)
- Yuen Yan Wong (ORCID: https://orcid.org/0000-0002-9567-5304)
Institutions
- Sunnybrook Health Science Centre (CA)
- University of Toronto (CA)
- Sunnybrook Research Institute
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.091588
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00