Geographic and ancestral variation in the association between <i>APOE</i> ε4 and cognitive function in South Asians from LASI‐DAD

Our results suggest that ancestral background may play a role in modulating the ε4 effects on cognitive function, contributing to the observed heterogeneity across Indian groups.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.092646
Primary Topic
Genetic Associations and Epidemiology
Type
article
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article

Geographic and ancestral variation in the association between APOE ε4 and cognitive function in South Asians from LASI‐DAD

Yi-Zhe Wang, Aparajit Ballav Dey, Alden L. Gross, Élise Kerdoncuff et al.
Alzheimer s & Dementia
Genetic Associations and Epidemiology
article

Geographic and ancestral variation in the association between APOE ε4 and cognitive function in South Asians from LASI‐DAD

Yi-Zhe Wang, Aparajit Ballav Dey, Alden L. Gross, Élise Kerdoncuff, Sharon L. R. Kardia, Xiang Zhou, Priya Moorjani, Sharmistha Dey, Jennifer A. Smith, Jinkook Lee, Zheng Li, Wei Zhao
article en

Abstract

Our results suggest that ancestral background may play a role in modulating the ε4 effects on cognitive function, contributing to the observed heterogeneity across Indian groups.

Alzheimer s & DementiaVol. 20(S1)
University of Southern California (US), Johns Hopkins University (US), University of Michigan (US), All India Institute of Medical Sciences (IN), University of California, Berkeley (US)
Quality Education
Openalex Percentile: Top 73%
Genetic Associations and Epidemiology
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