White matter hyperintensity onset, trajectories, and associations with cognitive decline in the presence of amyloid and tau
WMH accumulation follows a predictable trajectory post-onset and appears to exacerbate cognitive decline in those with amyloid pathology. Future analyses will further elucidate the complex relationships between vascular risk, amyloid, tau accumulation and cognitive decline.
Authors
- Bruce P. Hermann (ORCID: https://orcid.org/0000-0003-0133-4427)
- Tobey J. Betthauser (ORCID: https://orcid.org/0000-0001-8856-1352)
- Bradley Christian (ORCID: https://orcid.org/0000-0001-5072-3512)
- Sarah Hudson (ORCID: https://orcid.org/0000-0002-6217-110X)
- Lianlian Du
- Kevin M. Johnson (ORCID: https://orcid.org/0000-0002-8660-0853)
- Robert V. Cadman (ORCID: https://orcid.org/0000-0001-7685-1977)
- Elizabeth M. Planalp (ORCID: https://orcid.org/0000-0001-9219-0806)
- Aaron S. Field (ORCID: https://orcid.org/0000-0003-4349-1009)
- Erin M. Jonaitis (ORCID: https://orcid.org/0009-0004-5091-8255)
- Karly Alex Cody (ORCID: https://orcid.org/0000-0001-5996-2560)
- Leonardo A. Rivera‐Rivera (ORCID: https://orcid.org/0000-0001-5629-8721)
- Brenda Ryther
- Celena M. Ramsey
- Lisa Sparks
- Laura B. Eisenmenger (ORCID: https://orcid.org/0000-0001-6764-4239)
- Nathaniel A. Chin (ORCID: https://orcid.org/0000-0001-8008-9356)
- Nia Norris (ORCID: https://orcid.org/0000-0002-9651-7519)
- Howard A. Rowley (ORCID: https://orcid.org/0000-0002-3235-5792)
- Sterling C. Johnson (ORCID: https://orcid.org/0000-0002-8501-545X)
- Christian C. Pompa
- Ramiro Eduardo Rea Reyes (ORCID: https://orcid.org/0000-0001-9749-282X)
- Kimberly D. Mueller (ORCID: https://orcid.org/0000-0001-8691-9517)
- Sanjay Asthana (ORCID: https://orcid.org/0000-0002-3998-4479)
- Rebecca E. Langhough
- Beryl Miess
Institutions
- University of Wisconsin–Madison (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.089451
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00