Association of grip strength and gait speed with structural brain volume in older adults with and without cognitive impairment.
Grip strength and gait speed, both quick and easy clinical measures, are differentially related to structural brain volume. Grip strength is related to hippocampal volume only in male older adults with and without cognitive impairment, indicating potential influence of biological sex. Gait speed, however, is related to frontal lobe volume in both males and females. Changes in distinct measures of physical health of those with and without cognitive impairment may indicate changes in different regions of the brain.
Authors
- Kelsie M Full (ORCID: https://orcid.org/0000-0002-6264-0228)
- Timothy J. Hohman (ORCID: https://orcid.org/0000-0002-3377-7014)
- L. Taylor Davis
- Niranjana Shashikumar
- Hui Shi (ORCID: https://orcid.org/0009-0008-2864-1471)
- Keith R. Cole (ORCID: https://orcid.org/0000-0002-3573-3859)
- Kimberly R. Pechman (ORCID: https://orcid.org/0000-0003-0596-8064)
- Angela L. Jefferson
Institutions
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.091788
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00