Systems genetic dissection of Alzheimer’s disease brain gene expression networks

our cross-species, systems genetic approach establishes a putative causal chain linking AD pathology, large-scale gene expression perturbations, and ultimately, neurodegeneration.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.089491
Primary Topic
Alzheimer's disease research and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Systems genetic dissection of Alzheimer’s disease brain gene expression networks

Zhandong Liu, Pinghan Zhao, Juan Botas, Ismael Al‐Ramahi et al.
Alzheimer s & Dementia
Alzheimer's disease research and treatments
article

Systems genetic dissection of Alzheimer’s disease brain gene expression networks

Zhandong Liu, Pinghan Zhao, Juan Botas, Ismael Al‐Ramahi, Nicholas T. Seyfried, Allan I. Levey, Bismark K Amoh, Timothy Wu, Carl Grant Mangleburg, Aditi Sai Marella, Justin Dhindsa, Yarong Li, Omar El Fadel, Anh‐Tuan Le, Joshua M. Shulman
article en

Abstract

our cross-species, systems genetic approach establishes a putative causal chain linking AD pathology, large-scale gene expression perturbations, and ultimately, neurodegeneration.

Alzheimer s & DementiaVol. 20(S1)
Emory University (US), Baylor College of Medicine (US), Institute for Neurodegenerative Disorders (US), Neurological Research Institute (US), Texas Children's Hospital (US)
Life in Land
Openalex Percentile: Top 65%
Alzheimer's disease research and treatments
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Systems genetic dissection of Alzheimer’s disease brain gene expression networks — Zhandong Liu, Pinghan Zhao, et al. · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS