Microglia and extracellular vesicle‐mediated spread of Tau pathology

Microglia-specific targeting of Tsg101 show beneficial effect for ameliorating the disease progression of tauopathy mouse model via suppression of EV secretion, microglial activation, tau accumulation and complement-dependent synaptic pruning. Microglial Tsg101 is a potential therapeutic target of Alzheimer's disease and related tauopathy.

Authors

Tsuneya Ikezu (ORCID: https://orcid.org/0000-0002-3979-8596)

Institutions

WinnMed (US)
Mayo Clinic in Florida (US)

Publication Details

Journal: Alzheimer s & Dementia
Published: 2024-12-01
DOI: https://doi.org/10.1002/alz.087779
Citations: 1
Primary Topic: Extracellular vesicles in disease
Type: article
Field-Weighted Citation Impact: 0.23

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article

Microglia and extracellular vesicle‐mediated spread of Tau pathology

Tsuneya Ikezu

Dec 1, 2024

1 citations

Alzheimer s & Dementia

Extracellular vesicles in disease

0.23

article

Microglia and extracellular vesicle‐mediated spread of Tau pathology

Tsuneya Ikezu

December 1, 2024article en

1 citations

Abstract

Alzheimer s & DementiaVol. 20(S1)

WinnMed (US), Mayo Clinic in Florida (US)

Good health and well-being

Openalex Percentile: Top 40%

Extracellular vesicles in disease

0.23

DOI Open Access PDF OpenAlex

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Microglia and extracellular vesicle‐mediated spread of Tau pathology — Tsuneya Ikezu · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS