Identification of pathological pathways centered on circRNA dysregulation associated with early pathogenic progression of Alzheimer’s disease
Together, our results unveiled pathological brain circRNA landscape alterations within a critical window for phenotypic progression in a mouse model of AD and identified novel molecular mechanisms underlying dysregulation of conserved circRNA pathways that contribute to AD pathogenesis.
Authors
- Feng Wang
- Bing Yao (ORCID: https://orcid.org/0000-0002-6657-2760)
- Yue Feng (ORCID: https://orcid.org/0000-0002-7905-2182)
- Huifeng Shen (ORCID: https://orcid.org/0000-0002-8885-8778)
- Yangping Li (ORCID: https://orcid.org/0000-0002-3007-5826)
Institutions
- Emory University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.089983
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00