Beyond Traditional Measures: Exploring Cognitive Intraindividual Variability in Traumatic Encephalopathy Syndrome
The TES-CTE possible/probable group had the highest cognitive IIV with ∼23% dispersion (vs. ∼18-19% in TES-no and TES-CTE suggestive groups), suggesting greater cognitive variability in those with the greatest likelihood for having underlying CTE (based on TES criteria). This finding emphasizes the potential utility of exploring cognitive IIV as a method for detecting nuanced executive dysfunction in TES.
Authors
- Laura J. Balcer (ORCID: https://orcid.org/0000-0002-5136-4539)
- Caroline Altaras (ORCID: https://orcid.org/0000-0001-5347-9981)
- Douglas I. Katz (ORCID: https://orcid.org/0000-0002-7502-8505)
- Monica T. Ly (ORCID: https://orcid.org/0000-0002-4842-9047)
- Sarah Jane Banks (ORCID: https://orcid.org/0009-0001-6156-0605)
- Joseph Palmisano (ORCID: https://orcid.org/0000-0001-6000-3025)
- Charles H. Adler (ORCID: https://orcid.org/0000-0002-1045-2743)
- Robert C. Cantu (ORCID: https://orcid.org/0009-0002-4300-4063)
- Jennifer V. Wethe (ORCID: https://orcid.org/0000-0003-2911-1129)
- Charles Bernick (ORCID: https://orcid.org/0000-0003-4040-3587)
- Eric M. Reiman (ORCID: https://orcid.org/0000-0002-0705-3696)
- David W. Dodick (ORCID: https://orcid.org/0000-0002-9486-6790)
- Yonas E. Geda (ORCID: https://orcid.org/0000-0003-1187-7230)
- Michael L. Alosco (ORCID: https://orcid.org/0000-0002-8113-8428)
- William Barr (ORCID: https://orcid.org/0000-0001-7711-7758)
- Robert A. Stern (ORCID: https://orcid.org/0000-0002-5008-077X)
- Martha E. Shenton (ORCID: https://orcid.org/0000-0003-4235-7879)
- Brett Martin
- Jason Weller (ORCID: https://orcid.org/0000-0003-0387-5542)
- Yorghos Tripodis (ORCID: https://orcid.org/0000-0003-2190-7608)
- Jesse Mez (ORCID: https://orcid.org/0000-0003-1438-5442)
- Jeffrey L. Cummings
Institutions
- Boston University (US)
- Alzheimer's Association (US)
- Brigham and Women's Hospital (US)
- Translational Genomics Research Institute (US)
- Cleveland Clinic (US)
- Barrow Neurological Institute (US)
- University of Nevada, Las Vegas (US)
- University of Arizona (US)
- University of Phoenix (US)
- University of Washington (US)
- Lou Ruvo Brain Institute (US)
- University of California San Diego (US)
- Mayo Clinic in Arizona (US)
- Banner Alzheimer’s Institute
- Arizona Alzheimer’s Consortium
- Arizona State University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.092347
- Primary Topic
- Traumatic Brain Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00