Investigating the additive effects of Alzheimer’s disease biomarker staging and subjective cognitive decline in the prediction of clinical progression
SCD provides incremental information for the identification of individuals at high risk of imminent cognitive decline beyond a biomarker-based classification of AD pathology. In cognitively unimpaired individuals, the clinical stage should be taken into account additionally to AD biomarkers for an improved prediction of the time until clinical progression.
Authors
- Emrah Düzel (ORCID: https://orcid.org/0000-0002-0139-5388)
- Jens Wiltfang (ORCID: https://orcid.org/0000-0003-1492-5330)
- Robert Perneczky (ORCID: https://orcid.org/0000-0003-1981-7435)
- Annika Spottke (ORCID: https://orcid.org/0000-0001-9854-2972)
- Oliver Peters (ORCID: https://orcid.org/0000-0003-0568-2998)
- Stefan Johannes Teipel (ORCID: https://orcid.org/0000-0002-3586-3194)
- Elizabeth Kuhn (ORCID: https://orcid.org/0000-0002-3744-1155)
- Matthias Schmid (ORCID: https://orcid.org/0000-0002-0788-0317)
- Luca Kleineidam (ORCID: https://orcid.org/0009-0006-3309-6856)
- Michael Wagner (ORCID: https://orcid.org/0000-0003-2589-6440)
- Josef Priller (ORCID: https://orcid.org/0000-0001-7596-0979)
- Frank Jessen (ORCID: https://orcid.org/0000-0003-1067-2102)
- Julian Hellmann‐Regen (ORCID: https://orcid.org/0000-0003-0411-9204)
- Anja Schneider (ORCID: https://orcid.org/0000-0001-9540-8700)
- Michael T. Heneka (ORCID: https://orcid.org/0000-0003-4996-1630)
- Melina Stark (ORCID: https://orcid.org/0009-0005-3812-023X)
- Katharina Bürger (ORCID: https://orcid.org/0000-0002-4091-2755)
- Christoph Laske
Institutions
- University of Bonn (DE)
- University of Cologne (DE)
- University of Luxembourg (LU)
- University Hospital Bonn (DE)
- German Center for Neurodegenerative Diseases (DE)
- LMU Klinikum (DE)
- Humboldt-Universität zu Berlin (DE)
- Zimmer Biomet (Germany) (DE)
- Munich Cluster for Systems Neurology (DE)
- UK Dementia Research Institute (GB)
- Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (DE)
- Hertie Institute for Clinical Brain Research (DE)
- University of Rostock (DE)
- University of Aveiro (PT)
- Technical University of Munich (DE)
- University of Göttingen (DE)
- Freie Universität Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
- Ludwig-Maximilians-Universität München (DE)
- Otto-von-Guericke-Universität Magdeburg (DE)
- University of Edinburgh (GB)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.091377
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00