Multi‐omics assessment of genotype and sex‐specific effects of organochlorine pesticide DDT in humanized APOE mice

These data demonstrate gene-by-environment interactions modified by sex, providing a platform to investigate mechanisms in AD-related neurodegeneration and corroborating previous epidemiological findings.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.089489
Primary Topic
Metabolomics and Mass Spectrometry Studies
Type
article
Field-Weighted Citation Impact
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article

Multi‐omics assessment of genotype and sex‐specific effects of organochlorine pesticide DDT in humanized APOE mice

Isha Mhatre‐Winters, Jason R. Richardson, Young‐Mi Go, Ronald P. Hart et al.
Alzheimer s & Dementia
Metabolomics and Mass Spectrometry Studies
article

Multi‐omics assessment of genotype and sex‐specific effects of organochlorine pesticide DDT in humanized APOE mice

Isha Mhatre‐Winters, Jason R. Richardson, Young‐Mi Go, Ronald P. Hart, Jiada Zhan, Arturo Barahona, Yoonhee Han, ViLinh Tran, Dean P. Jones, Aseel Eid
article en

Abstract

These data demonstrate gene-by-environment interactions modified by sex, providing a platform to investigate mechanisms in AD-related neurodegeneration and corroborating previous epidemiological findings.

Alzheimer s & DementiaVol. 20(S1)
Rutgers, The State University of New Jersey (US), Emory University (US), University of Georgia (US), Florida International University (US)
Good health and well-being
Openalex Percentile: Top 78%
Metabolomics and Mass Spectrometry Studies
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