Neuroinflammatory Stress Exerts Distinct Proteomic Effects on Soma, Synapses and Mitochondria in Excitatory Neurons
Our neuron and synaptosome-enriched proteomics approach revealed unique molecular and signaling effects of neuroinflammation that may preferentially impact the synapses of excitatory neurons.
Authors
- Pritha Bagchi (ORCID: https://orcid.org/0000-0001-7229-9476)
- Claudia Espinosa‐García (ORCID: https://orcid.org/0000-0002-9909-9092)
- Srikant Rangaraju (ORCID: https://orcid.org/0000-0003-2765-1500)
- Nicholas T. Seyfried (ORCID: https://orcid.org/0000-0002-4507-624X)
- Victor Faúndez
- Prateek Kumar (ORCID: https://orcid.org/0000-0001-5875-4065)
- Duc Minh Duong (ORCID: https://orcid.org/0000-0001-5880-1888)
- Lihong Cheng (ORCID: https://orcid.org/0000-0002-2522-4831)
- Levi Benjamin Wood (ORCID: https://orcid.org/0000-0002-4248-0888)
- Upasna Srivastava (ORCID: https://orcid.org/0000-0003-4096-9257)
- Brendan Tobin (ORCID: https://orcid.org/0000-0003-1250-4356)
- Hailian Xiao (ORCID: https://orcid.org/0000-0002-3796-4693)
Institutions
- Georgia Institute of Technology (US)
- Emory University (US)
- Yale University (US)
- Institute for Neurodegenerative Disorders (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.090723
- Citations
- 1
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.25