Blood‐Based Biomarkers to Aid in Alzheimer’s Disease Prediction or Diagnosis: Analysis in a Multi‐Ethnic Cohort Study
While GFAP and P-tau181/Aβ42 levels are associated with AD pathology and can aid in the diagnosis of AD, the presence of multiple chronic conditions may lead to either false positives or negatives. Large multi-ethnic community cohort studies are needed to further examine the utility of these biomarkers in aiding in the clinical diagnosis of AD.
Authors
- Lawrence S. Honig (ORCID: https://orcid.org/0000-0002-9703-2265)
- Adam M. Brickman (ORCID: https://orcid.org/0000-0002-5125-8226)
- Jeffrey L. Dage (ORCID: https://orcid.org/0000-0002-2192-1699)
- Yian Gu (ORCID: https://orcid.org/0000-0002-4297-1548)
- Danurys Sanchez (ORCID: https://orcid.org/0000-0001-8273-0952)
- Jennifer J. Manly (ORCID: https://orcid.org/0000-0002-9481-7497)
- Richard P Mayeux (ORCID: https://orcid.org/0000-0001-6519-9696)
- Min Suk Kang (ORCID: https://orcid.org/0000-0002-8334-2262)
- Badri Narayan Vardarajan (ORCID: https://orcid.org/0000-0002-5560-4085)
- Dolly Reyes‐Dumeyer (ORCID: https://orcid.org/0000-0003-3572-8248)
- Rafael Lantigua (ORCID: https://orcid.org/0000-0003-4854-7331)
- Aanya Bahl
Institutions
- NewYork–Presbyterian Hospital (US)
- Columbia University Irving Medical Center (US)
- New York Hospital Queens (US)
- Institute on Aging (US)
- Indiana University (US)
- Columbia University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.091795
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00