Comprehensive aberrations of proteasome complex in Alzheimer’s disease

Taken together, our results present not only the impairment of the constitutive proteasome in AD, especially in neurons, at RNA and protein expression level, but also the impairment of its functionality.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.089220
Primary Topic
Ubiquitin and proteasome pathways
Type
article
Field-Weighted Citation Impact
0.00
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article

Comprehensive aberrations of proteasome complex in Alzheimer’s disease

Shan Jiang
Alzheimer s & Dementia
Ubiquitin and proteasome pathways
article

Comprehensive aberrations of proteasome complex in Alzheimer’s disease

Shan Jiang
article en

Abstract

Taken together, our results present not only the impairment of the constitutive proteasome in AD, especially in neurons, at RNA and protein expression level, but also the impairment of its functionality.

Alzheimer s & DementiaVol. 20(S1)
Columbia University Irving Medical Center (US)
Openalex Percentile: Top 78%
Ubiquitin and proteasome pathways
DOIOpen Access PDFOpenAlex
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Comprehensive aberrations of proteasome complex in Alzheimer’s disease — Shan Jiang · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS