Mitochondrial Calcium Uniporter Beta in Alzheimer’s Disease
This study demonstrates for the first time that modulating MCUB holds therapeutic promise in preserving bioenergetics and mitigating neuronal damage and AD progression. These findings have the potential to significantly advance our understanding of AD pathogenesis and pave the way for effective treatments for AD.
Authors
- Dhanendra Tomar (ORCID: https://orcid.org/0000-0002-3144-7257)
- John W. Elrod (ORCID: https://orcid.org/0000-0003-3925-2224)
- Sarah D Kaye
- Ashlesha Kadam (ORCID: https://orcid.org/0000-0003-4787-2597)
- Pooja Jadiya (ORCID: https://orcid.org/0000-0003-4807-9304)
- Darpan Raghav
Institutions
- Wake Forest University (US)
- Temple University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.086190
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00