Early molecular events of Autosomal Dominant Alzheimer’s Disease in marmosets with PSEN1 mutations
Marmosets carrying KI point mutations in PSEN1 provide the opportunity to study the earliest primate-specific mechanisms that contribute to the molecular and cellular root causes of AD onset and progression.
Authors
- Seung‐Kwon Ha
- Gregory W. Carter (ORCID: https://orcid.org/0000-0002-2834-8186)
- Takeshi Murai (ORCID: https://orcid.org/0000-0002-0429-4195)
- Afonso C. Silva (ORCID: https://orcid.org/0000-0002-6105-7567)
- Catrina Spruce
- Stacey J. Sukoff Rizzo (ORCID: https://orcid.org/0000-0002-1460-8127)
- Hasi Huhe
- Annat Haber (ORCID: https://orcid.org/0000-0001-8407-9171)
- Amantha Thathiah (ORCID: https://orcid.org/0000-0002-3132-4409)
- Gregg E. Homanics (ORCID: https://orcid.org/0000-0003-3641-8153)
- Brianne Stein
- Laura M. Schultz (ORCID: https://orcid.org/0000-0001-7506-8235)
- Lauren S. Bailey (ORCID: https://orcid.org/0000-0002-7155-5877)
- Peter L. Strick (ORCID: https://orcid.org/0000-0001-5794-8458)
- Sang‐Ho Choi (ORCID: https://orcid.org/0000-0002-4972-4531)
- Julia Oluoch
- Lauren Mongeau
- Anna Greenwood (ORCID: https://orcid.org/0000-0003-0605-431X)
- David J. Schaeffer (ORCID: https://orcid.org/0000-0003-2201-7092)
- Lauren K Hayrynen Schaeffer
- Jung Eun Park (ORCID: https://orcid.org/0009-0000-1474-0905)
- Ting Zhang
Institutions
- Tufts University (US)
- Sage Bionetworks (US)
- University of Pittsburgh (US)
- Jackson Laboratory (US)
- University of Maine (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.086608
- Primary Topic
- Advanced biosensing and bioanalysis techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00