Key role of ERβ in estrogenic regulation of neuronal mitochondrial function
ERβ exerts a pivotal role in maintaining neuronal mitochondrial function and bioenergetic homeostasis in female brain. Selectively activating ERβ could provide a precision medicine strategy to promote brain function in menopausal women while inhibiting breast tissue proliferation.
Authors
- Roberta Dı́az Brinton (ORCID: https://orcid.org/0000-0001-8450-772X)
- John W. McLean
- Zisu Mao
- Guoyuan Qi (ORCID: https://orcid.org/0000-0002-1742-7778)
- J. Brett Stanton
- Fei Yin (ORCID: https://orcid.org/0000-0002-7192-6308)
- Yuan Shang (ORCID: https://orcid.org/0000-0002-7093-4234)
- Tian Wang (ORCID: https://orcid.org/0000-0003-3296-0930)
- Shuhua Chen (ORCID: https://orcid.org/0000-0002-9178-5020)
Institutions
- University of Arizona (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.086633
- Citations
- 1
- Primary Topic
- Estrogen and related hormone effects
- Type
- article
- Field-Weighted Citation Impact
- 0.55