Association of CSF AD biomakers and lifestyle factors with neuropsychiatric symptoms among non‐demented older persons

These results suggest that level of cognitive reserve, sleep quality, and physical activity levels are associated with depression and other neuropsychiatric symptoms among non-demented older adults. Moreover, these associations differentially depend on AD-biomarker levels, suggesting that individualized approaches to the treatment of neuropsychiatric symptoms among older adults are likely most successful.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.088304
Primary Topic
Health, Environment, Cognitive Aging
Type
article
Field-Weighted Citation Impact
0.00
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Association of CSF AD biomakers and lifestyle factors with neuropsychiatric symptoms among non‐demented older persons

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Association of CSF AD biomakers and lifestyle factors with neuropsychiatric symptoms among non‐demented older persons

Anja Soldan, Marilyn Albert, Corinne Pettigrew, Abhay Moghekar, Adam P. Spira, Vadim Zipunnikov, Valerie Truesdell
article en

Abstract

These results suggest that level of cognitive reserve, sleep quality, and physical activity levels are associated with depression and other neuropsychiatric symptoms among non-demented older adults. Moreover, these associations differentially depend on AD-biomarker levels, suggesting that individualized approaches to the treatment of neuropsychiatric symptoms among older adults are likely most successful.

Alzheimer s & DementiaVol. 20(S3)
Johns Hopkins University (US), Johns Hopkins Medicine (US)
Openalex Percentile: Top 65%
Health, Environment, Cognitive Aging
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