Bilingualism contributes to resilience in distinct ADRD syndromes
These results point towards a protective, disease-specific effect of bilingualism in patients with AD-related neurodegenerative disease, supporting a role of bilingualism in resilience to ADRD. A strength of this study is its exploration of the effects of bilingualism in a largely autopsy-confirmed cohort of patients with distinct ADRD neuropathologies. The study may explain the mixed findings in previous studies of bilingualism's effects, emphasizing the need to explore the effect of bilingualism within specific ADRD subtypes. This may clarify the mechanism by which bilingualism modulates the course of ADRD and contributes to cognitive and brain resilience.
Authors
- Lawren VandeVrede (ORCID: https://orcid.org/0000-0002-8304-6711)
- Nina F. Dronkers (ORCID: https://orcid.org/0000-0003-4462-2963)
- Jonathan Tablante
- Jessica Deleon (ORCID: https://orcid.org/0000-0002-9779-0541)
- Stephanie M. Grasso (ORCID: https://orcid.org/0000-0001-5287-3012)
- Kaitlin Blackstone Casaletto (ORCID: https://orcid.org/0000-0001-5000-7604)
- Emily W. Paolillo (ORCID: https://orcid.org/0000-0003-4188-6998)
- Eugenie Mamuyac
Institutions
- University of California, San Francisco (US)
- University Memory and Aging Center (US)
- The University of Texas at Austin (US)
- University of California, Berkeley (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.093201
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00