Multi‐ancestry whole genome sequencing analysis of 36,361 individuals from the Alzheimer’s Disease Sequencing Project (ADSP)
A major goal of the ADSP is to fully reveal the genetic architecture of AD/ADRD across diverse ancestral populations with the hope that new discoveries and the therapeutic or prevention strategies they enable will benefit all ancestral groups. Complementary pooled-population and population-specific analyses of the ADSP's latest WGS data release are underway and new insights from these investigations are anticipated.
Authors
- Anita L. DeStefano (ORCID: https://orcid.org/0000-0002-9335-2819)
- Dongyu Wang
- Jiemin Yang (ORCID: https://orcid.org/0000-0002-6806-1673)
- John Farrell (ORCID: https://orcid.org/0000-0002-8726-5997)
- Bilçağ Akgün (ORCID: https://orcid.org/0000-0002-5220-5652)
- Congcong Zhu (ORCID: https://orcid.org/0000-0002-4035-1513)
- Seung Hoan Choi (ORCID: https://orcid.org/0000-0002-2797-3190)
- Xiaoling Zhang (ORCID: https://orcid.org/0000-0003-0868-1923)
- Adam C. Naj (ORCID: https://orcid.org/0000-0002-9621-2942)
- Eden R. Martin (ORCID: https://orcid.org/0000-0002-4035-9152)
- Brian W. Kunkle (ORCID: https://orcid.org/0000-0002-9515-5157)
- Andy Rampersaud (ORCID: https://orcid.org/0000-0002-1881-2731)
- Sven‐Thorsten Dietrich
- Kara L. Hamilton‐Nelson
Institutions
- Boston University (US)
- University of Miami (US)
- Dr. John T. Macdonald Foundation (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.092063
- Citations
- 2
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.10