Identifying medical phenotypes associated with microglia‐expressing AD risk genes
We demonstrated that in peripheral tissues enriched for macrophages, AD risk genes that function in microglia were associated with inflammatory phenotypes in directions consistent with that observed in microglia, suggesting shared immune biology.
Authors
- Bingshan Li (ORCID: https://orcid.org/0000-0003-2129-168X)
- Nancy Jean Cox (ORCID: https://orcid.org/0000-0001-9315-0830)
- Dan Zhou (ORCID: https://orcid.org/0000-0002-5313-8164)
- Xue Zhong (ORCID: https://orcid.org/0000-0002-7482-8471)
Institutions
- Vanderbilt University (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.093573
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00