Higher Cerebrovascular Reactivity Predicts Better Memory Function in Older Adults Without Dementia
In older adults without stroke or dementia, higher cerebrovascular reactivity is associated with better memory function. Cerebrovascular dysfunction is known to precede and contribute to the development of cognitive impairment. These findings suggest that cerebrovascular dysfunction influences cognitive performance even in preclinical stages. Future longitudinal may elucidate whether early cerebrovascular reactivity changes can predict long-term development of dementia.
Authors
- Daniel A. Nation (ORCID: https://orcid.org/0000-0002-9123-0658)
- Fatemah Shenasa (ORCID: https://orcid.org/0000-0001-9030-4857)
- Allison C Engstrom (ORCID: https://orcid.org/0000-0002-4676-0430)
- Shubir Dutt (ORCID: https://orcid.org/0000-0002-8408-2220)
- Xingfeng Shao (ORCID: https://orcid.org/0000-0002-4130-6204)
- John Paul M Alitin (ORCID: https://orcid.org/0009-0001-5494-9639)
- Danny J.J. Wang (ORCID: https://orcid.org/0000-0002-0840-7062)
- Arunima Kapoor (ORCID: https://orcid.org/0000-0003-4622-8951)
- Isabel J. Sible (ORCID: https://orcid.org/0000-0003-3922-0628)
- Aimée Gaubert (ORCID: https://orcid.org/0000-0001-6812-522X)
- Anisa Marshall (ORCID: https://orcid.org/0000-0001-5457-2520)
Institutions
- University of Southern California (US)
- University of California, Irvine (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.092009
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00