APOE4 Drives Liver/Brain Proteomic Shifts in Young Mice and Alters Metabolic Function Across iPSC‐Derived Hepatic and Neuronal Cells
These results begin to reveal the impacts of APOE genetic variation on metabolic function across hepatic and neuronal models. However, underlying mechanistic relationships still need to be elucidated.
Authors
- Edziu Franczak (ORCID: https://orcid.org/0000-0002-0845-4002)
- Jill K. Morris (ORCID: https://orcid.org/0000-0001-5911-4190)
- C. William Birky (ORCID: https://orcid.org/0000-0002-2025-1726)
- Heather Wilkins (ORCID: https://orcid.org/0000-0003-4563-4544)
- Colton R Lysaker
- Chelsea N. Johnson (ORCID: https://orcid.org/0000-0003-2827-3265)
- Paige C. Geiger (ORCID: https://orcid.org/0000-0002-3990-7246)
- John P. Thyfault (ORCID: https://orcid.org/0000-0001-7920-7466)
- Vivien Csikos Drummond
- Caleb A. Gilmore
Institutions
- University of Kansas (US)
- University of Kansas Medical Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.092482
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00