A weakly‐supervised, MRI‐guided clustering of cognitive decline: A post‐hoc analysis of the EXPEDITION‐3 clinical trial

Heterogeneity in brain atrophy is linked to distinct patterns of cognitive decline. Using longitudinal changes in MRI measures revealed decliner subgroups with greater difference in ADAS-cog scores compared to those obtained by baseline measures only.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.090535
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

A weakly‐supervised, MRI‐guided clustering of cognitive decline: A post‐hoc analysis of the EXPEDITION‐3 clinical trial

Ali Ezzati, Christos A. Davatzikos, İdris Demirsoy, Bhargav Teja Nallapu et al.
Alzheimer s & Dementia
Dementia and Cognitive Impairment Research
article

A weakly‐supervised, MRI‐guided clustering of cognitive decline: A post‐hoc analysis of the EXPEDITION‐3 clinical trial

Ali Ezzati, Christos A. Davatzikos, İdris Demirsoy, Bhargav Teja Nallapu, S. Ahmad Sajjadi, Kellen K. Petersen, Laura A. Rabin, Richard Lipton
article en

Abstract

Heterogeneity in brain atrophy is linked to distinct patterns of cognitive decline. Using longitudinal changes in MRI measures revealed decliner subgroups with greater difference in ADAS-cog scores compared to those obtained by baseline measures only.

Alzheimer s & DementiaVol. 20(S3)
Albert Einstein College of Medicine (US), City University of New York (US), University of California, Irvine (US), University of Pennsylvania (US), Brooklyn College (US)
Openalex Percentile: Top 66%
Dementia and Cognitive Impairment Research
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A weakly‐supervised, MRI‐guided clustering of cognitive decline: A post‐hoc analysis of the EXPEDITION‐3 clinical trial — Ali Ezzati, Christos A. Davatzikos, et al. · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS