Differential Patterns of Gut and Oral Microbiomes in Patients with Mild‐cognitive Impairment
Our results suggest that the saliva microbiome, like the gut microbiome, is disrupted as patients progress from NC to MCI. The pathogenic oral microbes we found were previously linked to periodontal and gingivitis pathogens. Further studies with larger sample sizes are needed to validate these findings.
Authors
- Sudha S. Seshadri (ORCID: https://orcid.org/0000-0001-6135-2622)
- Yannick N. Wadop (ORCID: https://orcid.org/0000-0002-8955-1874)
- Julia J Mathews
- Gladys E. Maestre (ORCID: https://orcid.org/0000-0002-0020-8042)
- Michael C. Mahaney (ORCID: https://orcid.org/0000-0002-1341-3950)
- Tiffany F. Kautz (ORCID: https://orcid.org/0000-0001-7680-4708)
- Bernard Fongang (ORCID: https://orcid.org/0000-0002-8161-1553)
- Jazmyn A Muhammad
- Rosa P. Pirela‐Mavarez
Institutions
- Boston University (US)
- The University of Texas at San Antonio Health Science Center (US)
- The University of Texas Rio Grande Valley (US)
- Institute for Neurodegenerative Disorders (US)
- Framingham Heart Study (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.089090
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00