Modulation of Autophagy and mTOR pathways by Metformin in Olfactory Neuroepithelial Cells Across Different Age Groups: Insights into Pharmacological Implications for Neurodegeneration
Our data showed that MET treatment inhibits mTOR signaling and enhances the autophagy pathway in NS/PCs-OE from non-diabetic aged subjects.
Authors
- María del Carmen Cárdenas‐Aguayo (ORCID: https://orcid.org/0000-0001-9156-2161)
- Maria‐del‐Carmen Silva‐Lucero (ORCID: https://orcid.org/0000-0002-2272-0610)
- Laura Gomez‐Virgilio (ORCID: https://orcid.org/0000-0001-7765-8159)
- Obed‐Ricardo Lora‐Marin
Institutions
- Universidad Nacional Autónoma de México (MX)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.093304
- Primary Topic
- Olfactory and Sensory Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00