Higher amyloid burden is associated with faster reduction in cerebral blood flow: a longitudinal study
Our results demonstrate that longitudinal CBF changes are strongly associated with baseline SUVR levels both globally and regionally, suggesting that increased amyloid burden may affect neurological dysfunction leading to CBF reduction over time.
Authors
- Meredith N. Braskie (ORCID: https://orcid.org/0000-0002-6439-4243)
- Jianing Tang (ORCID: https://orcid.org/0000-0001-9079-5799)
- Vasilis Z. Marmarelis (ORCID: https://orcid.org/0000-0003-1457-813X)
- Elizabeth Joe (ORCID: https://orcid.org/0000-0002-5222-0772)
- Lirong Yan (ORCID: https://orcid.org/0000-0002-5173-7059)
- Helena C. Chui (ORCID: https://orcid.org/0000-0003-1348-0931)
- Tianrui Zhao (ORCID: https://orcid.org/0009-0007-0889-5629)
- Jamie Terner
Institutions
- Northwestern University (US)
- University of Southern California (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.093317
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00