Differential Pattern of Tau Deposition is Associated with Each Cognitive Score in Cognitively Unimpaired Elders
Our findings provide evidence for regional specificity of tau deposition in unimpaired elders, as it has been reported in AD patients. In addition, while the presence of Aβ strongly modulates the relationship between tau and memory, this modulation is significantly attenuated or completely missing from other cognitive domains.
Authors
- Siddharth Nayak (ORCID: https://orcid.org/0000-0002-5822-1119)
- Sindy Ozoria
- Qolamreza Razlighi (ORCID: https://orcid.org/0000-0001-9588-8062)
- Bardiya Ghaderi
- Seyed Hani Hojjati (ORCID: https://orcid.org/0000-0003-3900-9603)
- Peter Chernek
- Jenseric Calimag
Institutions
- Cornell University (US)
- Weill Cornell Medicine (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.090023
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.39