Dyadic patterns of subjective cognitive decline and longitudinal cognitive outcomes
The direction of dyadic discrepancy related differently to diagnostic conversion and cognitive performance. Greater self-reported SCD related to greater likelihood of diagnostic conversion in cognitively unimpaired participants. However, greater informant-reported SCD related to worsening cognitive performance. Results highlight that dyadic patterns of SCD differentially predict prognosis and incorporation of an informant provides important information. Further analyses will examine dyadic discrepancy and longitudinal biomarker patterns.
Authors
- Timothy J. Hohman (ORCID: https://orcid.org/0000-0002-3377-7014)
- Michelle L Houston (ORCID: https://orcid.org/0009-0001-9031-2459)
- Angela Lee Jefferson (ORCID: https://orcid.org/0000-0002-8245-0587)
- Kimberly R. Pechman (ORCID: https://orcid.org/0000-0003-0596-8064)
- Dandan Liu (ORCID: https://orcid.org/0000-0002-4635-0087)
- Panpan Zhang (ORCID: https://orcid.org/0000-0002-8211-5930)
- Katherine A. Gifford (ORCID: https://orcid.org/0000-0001-6232-9408)
Institutions
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.087053
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00