Red Light Therapy Attenuates Prolonged LED light Exposure‐Associated Neuropathology and Mediates Circadian Clock Genes ‐ <i>Per</i>1 and <i>Bmal</i>1 Expression in Rats' Basal Ganglia

The findings from this study revealed that red light therapy attenuates LED light-exposure-induced anxiogenic responses and Per1 gene expression impairment. Consequently, these findings have the potential to inform the development of non-invasive treatment strategies targeting the improvement of sleep quality in the management of neurodegenerative disorders. However, safety assessments should be ensured for its validation.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.084765
Primary Topic
Photoreceptor and optogenetics research
Type
article
Field-Weighted Citation Impact
0.00
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article

Red Light Therapy Attenuates Prolonged LED light Exposure‐Associated Neuropathology and Mediates Circadian Clock Genes ‐ Per1 and Bmal1 Expression in Rats' Basal Ganglia

Pius A. Okiki, Adejoke Olukayode Obajuluwa, Tiwalola Madoc Obajuluwa, James C. Lech et al.
Alzheimer s & Dementia
Photoreceptor and optogenetics research
article

Red Light Therapy Attenuates Prolonged LED light Exposure‐Associated Neuropathology and Mediates Circadian Clock Genes ‐ Per1 and Bmal1 Expression in Rats' Basal Ganglia

Pius A. Okiki, Adejoke Olukayode Obajuluwa, Tiwalola Madoc Obajuluwa, James C. Lech, Laoye John Babafemi, Ogochukwu Jessica Ndianefo
article en

Abstract

The findings from this study revealed that red light therapy attenuates LED light-exposure-induced anxiogenic responses and Per1 gene expression impairment. Consequently, these findings have the potential to inform the development of non-invasive treatment strategies targeting the improvement of sleep quality in the management of neurodegenerative disorders. However, safety assessments should be ensured for its validation.

Alzheimer s & DementiaVol. 20(S1)
Afe Babalola University (NG)
Good health and well-being
Openalex Percentile: Top 74%
Photoreceptor and optogenetics research
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