A digital brain sampling protocol atlas to simplify and accelerate biorepository tissue requests

The digital BSP atlas provides a quantitative representation of the BSP in a standard space which will accelerating the process of requesting brain tissue, allows for the refinement of protocols, and the coordination of neuroimaging information with neuropathology sample. Future directions of this work include customizable visualizations, training software, and website backend to identify corresponding samples from free-form text with arbitrary neuroscience terms. This research is part of a pipeline to facilitate mechanistic understanding of AD by enhancing the precision and accuracy of neuropathology sampling and robust registration to premortem neuroimaging data even for late-stage AD participants.