Plasma high‐density lipoprotein levels is associated with preserved hippocampal volume in Alzheimer`s disease individuals without vascular co‐pathology
We showed that high plasma HDL levels is associated with less white matter pathology and reduced hippocampal atrophy scores, without changing plasma NfL levels. Together our findings indicate that high HDL levels seem to be associated with preserved brain volume only in AD individuals with no vascular co-pathology.
Authors
- Hyun Woong Roh (ORCID: https://orcid.org/0000-0002-1333-358X)
- Chang‐Hyung Hong
- Dana Tudorascu (ORCID: https://orcid.org/0000-0003-4675-3692)
- Helmet T. Karim (ORCID: https://orcid.org/0000-0002-9286-0694)
- Madeleine Bloomquist (ORCID: https://orcid.org/0009-0009-0556-9478)
- Tharick Ali Pascoal (ORCID: https://orcid.org/0000-0001-9057-8014)
- Cynthia Felix (ORCID: https://orcid.org/0000-0002-4283-4498)
- Guilherme Povala (ORCID: https://orcid.org/0000-0002-2023-6569)
- Eduardo Rigon Zimmer (ORCID: https://orcid.org/0000-0002-5349-0053)
- Carolina Soares (ORCID: https://orcid.org/0000-0002-2338-4495)
- Sang Joon Son (ORCID: https://orcid.org/0000-0001-7434-7996)
- Guilherme Bauer‐Negrini (ORCID: https://orcid.org/0000-0003-0956-557X)
- Pâmela C.L. Ferreira (ORCID: https://orcid.org/0000-0003-2134-9829)
- Matheus Scarpatto Rodrigues (ORCID: https://orcid.org/0000-0002-7794-6588)
- Thomas K. Karikari (ORCID: https://orcid.org/0000-0003-1422-4358)
- Bruna Bellaver (ORCID: https://orcid.org/0000-0002-2212-3373)
- Sarah Abbas
- Firoza Zubeida Lussier (ORCID: https://orcid.org/0000-0002-6877-4825)
- Hussein Zalzale
- Markley Silva Oliveira (ORCID: https://orcid.org/0000-0002-0631-4065)
- Jade de Oliveira (ORCID: https://orcid.org/0000-0003-1454-2866)
- Pampa Saha (ORCID: https://orcid.org/0000-0002-4926-9081)
- Marina Scop Madeiros
Institutions
- Universidade Federal do Rio Grande do Sul (BR)
- University of Pittsburgh (US)
- Ajou University Hospital (KR)
- Ajou University (KR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.092693
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00