Task‐related brain activation moderates age‐related structural decline in cognitive flexibility: A longitudinal study
Older adults utilizing task-related functional brain networks to meet increasing demands showed attenuation of effects of structural decline on reducing cognitive flexibility over time. Results suggest differential activation of identified functional networks, serving as a neural implementation of CR, elucidating neuroprotective factors that preserve executive functions into advanced age.
Authors
- Elaine Gazes
- Fatemeh Hasanzadeh (ORCID: https://orcid.org/0000-0002-8064-7220)
- Yaakov Stern (ORCID: https://orcid.org/0000-0001-7542-3241)
- Christian Habeck (ORCID: https://orcid.org/0000-0001-9961-7446)
Institutions
- Columbia University Irving Medical Center (US)
- Columbia University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.092613
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00