Behavioral and Molecular Consequences of Pathogenic Tau Expression in Mouse Locus Coeruleus
At 3 months, anxiety- and compulsive-like behaviors and hypersomnia phenotypes suggest dysregulation of LC-NE transmission. Further studies are ongoing to assess the cellular and molecular mechanisms governing these behavioral symptoms in early AD.
Authors
- Anuradha Korukonda
- Margaret M. Tish (ORCID: https://orcid.org/0000-0002-8954-1983)
- Joseph Atallah (ORCID: https://orcid.org/0000-0001-8763-2067)
- David Weinshenker (ORCID: https://orcid.org/0000-0002-3678-6215)
Institutions
- Emory University (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1002/alz.090727
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00