The involvement of human CD33 in the pathogenesis of Alzheimer’s disease mouse model

Our findings suggested that the presence of the AD risk gene human CD33 incurred neurotoxicity and altered the structure of Aβ deposition by manipulating microglial barrier formation against AD stress.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2024-12-01
DOI
https://doi.org/10.1002/alz.086747
Primary Topic
14-3-3 protein interactions
Type
article
Field-Weighted Citation Impact
0.00
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article

The involvement of human CD33 in the pathogenesis of Alzheimer’s disease mouse model

Wei‐Chien Hung, Irene Han‐Juo Cheng, Tzu‐Ching Su
Alzheimer s & Dementia
14-3-3 protein interactions
article

The involvement of human CD33 in the pathogenesis of Alzheimer’s disease mouse model

Wei‐Chien Hung, Irene Han‐Juo Cheng, Tzu‐Ching Su
article en

Abstract

Our findings suggested that the presence of the AD risk gene human CD33 incurred neurotoxicity and altered the structure of Aβ deposition by manipulating microglial barrier formation against AD stress.

Alzheimer s & DementiaVol. 20(S1)
National Yang Ming Chiao Tung University (TW)
Openalex Percentile: Top 78%
14-3-3 protein interactions
DOIOpen Access PDFOpenAlex
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The involvement of human CD33 in the pathogenesis of Alzheimer’s disease mouse model — Wei‐Chien Hung, Irene Han‐Juo Cheng, et al. · Alzheimer s & Dementia (2024) | TGRS Research Map | TGRS